Exposure to Polybrominated Diphenyl Ethers and Risk of Thyroid Cancer in Women

Polybrominated diphenyl ethers: occurrence, dietary exposure, and toxicology.

Polybrominated diphenyl ethers (PBDEs) are used as flame retardants in plastics (concentration, 5--30%) and in textile coatings. Commercial products consist predominantly of penta-, octa-, and decabromodiphenyl ether mixtures, and global PBDE production is about 40,000 tons per year. PBDEs are bioaccumulated and biomagnified in the environment, and comparatively high levels are often found in a...

Polybrominated diphenyl ethers and polybrominated biphenyls in Australian sewage sludge.

This paper presents a brief review of the international scientific literature of polybrominated diphenyl ethers (PBDEs) and polybrominated biphenyls (PBBs) in sewage sludge and a survey of these compounds in sewage sludge from 16 Australian wastewater treatment plants (WWTPs). The SigmaPBDE mean concentration in the Australian study was 1137microgkg(-1) dry weight (d.w.) (s.d. 1116) and ranged ...

Polybrominated diphenyl ethers and thyroid cancer risk in the Prostate, Colorectal, Lung, and Ovarian Cancer Screening Trial cohort.

Polybrominated diphenyl ethers (PBDEs) alter thyroid hormone homeostasis, but their relationship with thyroid cancer is unknown. To investigate whether serum concentrations of PBDE were associated with thyroid cancer, we conducted a nested, case-control study in the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial, a large multicenter clinical trial in the United States. Cases wit...

Polybrominated Diphenyl Ethers in the Canadian Environment

Polybrominated diphenyl ethers in UK human milk

24 Fourteen tri-deca polybrominated diphenyl ethers (PBDEs) were investigated in 35 human 25 milk samples from Birmingham, UK. While none of the hepta-nona BDEs (the main 26 components of the OctaBDE technical mixture) were above the limit of quantitation (LOQ); 27 BDE-47 (average concentration = 3.3 ng g lipid weight (lw)) was quantified in all samples 28 contributing 34-74% to Σtri-hexa BDEs ...